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Hib Focus Newsletter

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Hib in the News

DAWN News (Pakistan): Children of a lesser god
26 July 2008

Solomon Times (Solomon Islands): Five diseases in one shot
18 July 2008

Panacea Biotec News Release (India): Panacea Biotec pre-qualified by WHO for supply of Pentavalent Vaccine, EasyFive* to UN agencies
About Panacea EasyFive
10 July 2008

Reuters (India): Panacea gets WHO prequalification for vaccine
10 July 2008

Afrique en ligne: Togo includes Pentavalent vaccine in immunisation programme
04 July 2008

The Jakarta Post (Indonesia): Pneumonia: Indonesia’s forgotten child killer
3 July 2008

DAWN News (Pakistan): New infant vaccine to be available from August
25 June 2008

The Cambodian Daily: We Must Work To Protect Children From Infectious Diseases
17 June 2008

Australia and Papua New Guinea launch efforts to crush deadly Hib disease in Pacific region
10 April 2008

Countdown 2015 use of Hib vaccine as an indicator
10 April 2008

Statement by Julian Lob-Levyt, GAVI Alliance Executive Secretary
10 April 2008

The East African: Saving the Kids (March 31, 2008)

Deadly Disease Eliminated in Children under Five Years of Age in Uganda
Nearly 100 Percent Drop in Hib Meningitis as a Result of Widespread Vaccination (March 10, 2008)

WHO reports on accelerated Hib vaccine progress in low income countries (February 15, 2008)

CDC reports on progress of Hib vaccine introduction in MMWR (February 15, 2008)

More Children in Low-Income Countries Getting Vaccinated Against Hib Pneumonia and Meningitis
Vaccine use increasing in places where most Hib disease and deaths occur (February 14, 2008)

Give kids a chance to live, an opinion editorial by Dr. Mathuram Santosham, professor of International Health at Johns Hopkins Bloomberg School of Public Health and professor of Pediatrics at Johns Hopkins Medical School in Baltimore, Md. (December, 2007)

Global Framework for Immunization Monitoring and Surveillance (GFIMS) was published by the World Health Organization (WHO) (December 2007)
This document on the global framework has two target audiences: country-level program and surveillance decision-makers and planners, and organizations that fund immunization programs.

Sri Lanka to introduce DTP-HebB-Hib pentavalent vaccine in 2008 (2 newspaper articles, December 2007)

Working Together to Protect Children’s Health, an opinion editorial by Dr. Khuri-Bulos, Chairman of the Department of Pediatrics, Jordan University Hospital, Amman, and Dr. Hajjeh, director of the Hib Initiative (December, 2007)

Focus Alert: GAVI approves US$ 369.98 million support for introduction of Hib vaccine in 16 countries (November 29, 2007)

GAVI Alliance announcement: approval of US$ 537.52 million for critically needed vaccines and health system support (November 29, 2007)

First Year Results: IFFIM Provides US$ 1 Billion to Prevent Disease

International Vaccine Institute (IVI) and the Democratic People's Republic of Korea introduce Hib and JE vaccines for children

India launches new Hib vaccine
Press release of Bharat Biotech's launch of new Hib conjugate vaccine (September 3, 2007)

Fighting for the World’s Children – a Call to Action
Opinion Editorial from Dr. Adenike Grange, Honorable Minister of Health, Nigeria and President of the International Pediatric Association (August 31, 2007)

Economic evaluation of delivering Haemophilus influenzae type b vaccine in routine immunization services in Kenya (July 6, 2007)

Hib vaccine: A critical ally in Asia’s effort to reduce child deaths
New study shows Hib vaccine protects children from significant burden of life-threatening pneumonia and meningitis (June 27, 2007)
Study Facts on the Hib Case-Control Study in Asia (July 26, 2007)

Introduction of Haemophilus influenzae type B conjugate vaccine into routine immunization in Ghana and its impact on bacterial meningitis in children younger than five years (June 12, 2007)

News from Poland: Implementation of universal infant vaccination with Hib conjugate vaccine in Poland (May 7, 2007)

Serum Institute of India obtains first ever Indian license for its monovalent Hib vaccine developed through technology transfer from the Netherlands Vaccine Institute (May 3, 2007)

The Daily Star (Bangladesh): It’s time to save more children from early grave
22 April 2007

Increasing Immunization Rates and New Vaccine Offer Hope for Ethiopian Children (April 3, 2007)

The Daily Star (Bangladesh): Meeting to highlight burden of meningitis and pneumonia
01 April 2007

Thai Ministry of Public Health and WHO Host Meeting of Leading Researchers to Highlight Burden of Meningitis and Pneumonia (March 29, 2007)

From Pandemic Suspect to the Postvaccine Era: The Haemophilus influenzae Story (March 26, 2007)

The epidemiology of pneumococcal, meningococcal, and Haemophilus disease in the Middle East and North Africa (MENA) Region-Current status and needs (February 8, 2007)

BBC Documentary TeaserGroundbreaking BBC World documentaries to focus on health & vaccines in the developing world (February 5, 2007)

Sierra Leone to introduce Hib Vaccine (January 11, 2007)

Cambridge Biostability, U.K. and Panacea Biotec, India sign Joint Venture and Licensing agreement
Cambridge Biostability, U.K. and Panacea Biotec, India sign Joint Venture and Licensing agreement to produce and market a stable liquid version of a pentavalent vaccine for the treatment of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus Influenza type B.
Panacea Biotec | 6 December 2006

New Hib advocacy presentation now available (December 11, 2006)

GAVI Alliance Announces Funding for New Vaccines Against Two Major Killers of Children in Poorest Nations (November 29, 2006)
GAVI Alliance Board approved a first investment of US$200 million to help an initial group of developing countries introduce newly licensed vaccines against rotavirus and pneumococcus. GAVI's investments will increase over time as more experience is gained and an increasing number of countries adopt the vaccine.

FOCUS ALERT: Updated WHO Position Paper: Routine Hib Immunization For All Infants (November 27, 2006)

FOCUS ALERT: A New Phase of Funding To Support Life-Saving Vaccines: Hib, Hepatitis B, yellow fever and measles* vaccines (November 17, 2006)

Report reveals that pneumonia kills more children under five than any other illness (September 18, 2006)
A report launched today by the WHO and UNICEF reveals that pneumonia kills more children under five than any other illness – more than AIDS, malaria and measles combined.

India’s Minister of Health Discusses Hib Vaccine (September 7, 2006)
Johns Hopkins Bloomberg School of Public Health received a visit from India’s Minister of Health, Honorable Anbumani Ramadoss. In an interview with Dr. Santosham, Professor of International Health at Hopkins, Ramadoss discussed the burden of pneumonia and the importance of the Hib vaccine.

JAMA Reports on Kenya Hib Surveillance Study (August 9, 2006)
This study reports on hospital-based surveillance of invasive Hib disease in Kilifi Kenya prior to and following routine immunization of infants with Hib vaccine. The surveillance showed an 88% drop in invasive Hib disease incidence 3 years after the pentavalent vaccine (DTP-HepB-Hib) was included as part of EPI schedule for infants. Invasive disease incidence dropped from 66/100,000 pre-vaccine to 7.6 /100,000 three years later. The authors estimate that 3370 hospitalizations of the 5.8 million children in Kenya were also averted.
* Effectiveness of Haemophilus influenzae Type b Conjugate Vaccine Introduction Into Routine Childhood Immunization in Kenya. JAMA. 2006;296:671-678

Cuba Produces Key Synthetic Vaccine for Children
Cuban researchers have developed the first synthetic vaccine against a bacteria that causes pneumonia and meningitis, a breakthrough aimed at lowering the cost of immunizing children in poorer countries.
Reuters | 8 August 2006

Global Immunization Vision and Strategy (GIVS)
In response to challenges in global immunization, WHO and UNICEF developed the Global Immunization Vision and Strategy, 2006-2015 [pdf 3.5Mb]. In brief, GIVS aims to immunize more people, from infants to seniors, with a greater range of vaccines. Its chief goal is to, by 2015 or earlier, reduce illness and death due to vaccine-preventable diseases by at least two thirds compared to 2000 levels.

Malawi Hib Vaccine Impact Study
This study reports on hospital surveillance of acute bacterial meningitis in children under 5 from 1997 - 2005. After Hib conjugate vaccine introduction in 2002, meningitis rates dropped from 20-40/100,000 to near zero in 2004 and 0 in 2005. Data also document drops in wastage and increases in coverage following the introduction of pentavalent vaccine. (View in PDF Format)
Vaccine. 2006 Jun 9

WHO supporting Ethiopia with introduction of new childhood vaccines
Life saving vaccines against hepatitis B (Hep B) and Haemophilus influenzae type b (Hib) will soon be introduced in Ethiopia. These vaccines have been used in many countries for some time. However, despite a high disease burden of these vaccine preventable diseases, Ethiopian children have not had access to these important vaccines.
Lancet Infect Dis 2006; 6: 150–61

Lancet review article regarding bacterial pneumonia
Bacterial pneumonia is a substantial cause of childhood morbidity and mortality worldwide, but determination of pathogen-specific burden remains a challenge. In less developed settings, the WHO recommended guidelines are useful for initiating care, but are non-specific. Blood culture has low sensitivity, while radiological findings are nonspecific and do not discriminate between viral and bacterial causes of pneumonia.
Lancet Infect Dis 2006; 6: 150–61

A meta-analysis of vaccine efficacy
Haemophilus influenzae type b (Hib) infection is a leading cause of meningitis and pneumonia in infants and children in the developing countries, and yet the implementation of routine Hib vaccination is very slow.The aim of the present study was to quantify the protective efficacy of H. influenzae type b vaccination of young children. MEDLINE, EMBASE, and the Cochrane Central.
Eur J Clin Microbiol Infect Dis

Hib Vaccine Could Reduce Major Childhood Diseases
Hib disease annually causes an estimated 3 million cases of serious illness and 400,000 deaths. But despite the availability of financing for Hib vaccination, writes Lois Privor-Dunn of the Hib Initiative at Johns Hopkins University, most countries have not introduced the vaccine, leaving three-quarters of the world's children at risk
http://www.prb.org/HIB

Children to be given new vaccine
A vaccine which protects against a disease that causes blood poisoning, meningitis and pneumonia is being added to the UK child immunisation programme. Up to 50 children under two are thought to die in England and Wales a year from serious pneumococcal infections. Chief Medical Officer Sir Liam Donaldson said the new vaccine would save lives and prevent hundreds of serious illnesses in the young and old. The three-dose jab will be introduced in 2006/2007, it has been confirmed. The changes set out today will further improve the programme.
BBC NEWS: http://news.bbc.co.uk/go/pr/fr/-/1/hi/health/4692908.stm

Prevention of Haemophilus influenzae type b disease: past success and future challenges
Haemophilus influenzae type b (Hib) is responsible for significant morbidity and mortality worldwide, particularly in children under 5 years of age. In countries where the Hib conjugate vaccine is not routinely used, Hib is a leading cause of childhood pneumonia and meningitis. Routine use of the Hib conjugate vaccines has resulted in a remarkable decline in Hib disease.
Aruna Chandran, James P Watt and Mathuram Santosham

Characteristics of Haemophilus influenzae type b responsible for meningitis in Poland from 1997 to 2004.
Life saving vaccines against hepatitis B (Hep B) and Haemophilus influenzae type b (Hib) will soon be introduced in Ethiopia. These vaccines have been used in many countries for some time. However, despite a high disease burden of these vaccine preventable diseases, Ethiopian children have not had access to these important vaccines.
(ReliefWeb | 10 February 2006) - Hib and hep B

Haemophilus influenzae type b (Hib) -SAGE reccomendations
SAGE reviewed the morbidity and mortality of Hib pneumonia and meningitis in Africa and Asia and current national immunization recommendations against Hib disease. It also reviewed the GAVI Hib initiative whose purpose is to reduce the risk of childhood death and disability through sustained use of the vaccine. In countries that use Hib vaccine, the results of analyses indicate a significant reduction in pneumonia and meningitis, resulting in decreased use of health services for the treatment of these diseases.
Weekly Epidemiologic Record

Funds for vaccination over next decade may fall short by $10bn
The cost of vaccinating children in the world’s 72 poorest countries over the next decade would be $35bn (Ł20bn; €29bn), a new study by the World Health Organization and Unicef says. The study, which was released last week in New Delhi at the third partners’ meeting of the Global Alliance for Vaccines and Immunisation, has estimated.
BMJ 2005;331:1426 (17 December), doi:10.1136/bmj.331.7530.1426-f News Extra

Norway pledges one billion dlrs to vaccine programme
NEW DELHI - Norway's Prime Minister Jens Stoltenberg Wednesday said his government would give one billion dollars over the next 10 years to support a global immunisation programme. "It is unnecessary and unacceptable that a child dies every third second, that more than 26,000 children die every day," Stoltenberg told the inaugural session of a three-day international vaccine meeting.
(Agence France Presse | 7 December 2005)

Global health experts urge early immunisation
New Delhi - An early decision on including vaccines for diseases like meningitis and pneumonia in the immunisation programme can help save millions of infant lives, global experts said here Thursday. "These are vaccine preventable diseases that would not only save lives but also reduce the disease burden on the government while ensuring better lives and economic benefits for the family," said John R. Wecker.
(IANS x 8 December 2005)

Low-cost immunisation could save another 10 million, says UN
New Delhi: Ten million additional lives could be saved through child and maternal immunisation between 2006-2015 at an average annual cost of US $1 billion, according to a new study by the World Health Organisation (WHO) and UNICEF. The estimated US $2.5 billion current annual spending on immunisation in the poorest countries would need to increase to US $3.5 billion by 2010 and US $4 billion by 2015 to reach this goal.
(OneWorld UK | 9 December 2005) - press release verbatim http://uk.oneworld.net/article/view/123705/1/

Scientists discuss new vaccines
New Delhi - Health experts from around the world were to meet in New Delhi on Thursday to assess progress made in developing new vaccines to fight killer diseases among children in the world's poorest countries.... & ....Health experts from around the world were to meet in New Delhi on Thursday to assess progress made in developing new vaccines to fight killer diseases among children in the world's poorest countries.
(News24 (South Africa) | 8 December 2005) & (Pravda/News from Russia | 8 December 2005)

Overloaded healthcare systems main barriers to vaccination
More and more children are dying of preventable diseases in 14 mostly African countries torn by civil strife or whose health care systems are overloaded by the AIDS crisis, the head of the UNICEF said Thursday, urging developed countries to take action. Rich nations need to "find ways to assist countries in crisis or other fragile states," said executive director Ann Veneman at a meeting
(Pravda/News from Russia | 8 December 2005)

Bill Gates vows to 'crack' vaccine gap (Indian Express | 8 December 2005)
With 27 million children missing out on immunisation in their first year and 1.4 million dying of vaccine-preventable diseases by the age of 5, Microsoft Chairman Bill Gates insisted on "cracking the historic gap between the development of the vaccine and implementation in the developing world".

 

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